PostDoc position: Novel synthetic biology parts for sustainable protein production in the yeast Komagataella phaffii

That’s the project

The production of recombinant proteins used as biopharmaceuticals, industrial enzymes and novel animal protein replacement in nutrition is of paramount importance for both public health and a sustainable bio-based economy. Improving the biological production platforms, including the yeast Pichia pastoris (syn Komagataella phaffii), is an important tool to make bioprocesses sustainable in the long term and at the same time economically competitive. The aim of this project is to develop novel parts and genetic tools that allow for regulatable gene expression, while avoiding the use of hazardous substances.

Such parts will be identified by systems biology approaches (omics). Cloning and genetic manipulations will be carried out using state-of the art-methods such as Golden Gate Assembly and CRISPR/Cas9-based homology directed recombination (HDR). The resulting strains will be characterized for growth and productivity in high throughput screening and bioreactor cultivations.

That could be your future

You are working in an enjoyable work climate, have numerous possibilities for further education and personal development. You are part of a challenging and helpful work environment full of team spirit and enthusiasm for your job. You expand your expertise and bridge your science to industry.

We offer you fully flexible working hours and a package of voluntary social benefits (e.g. meal vouchers or tickets for public transport) are also part of our modern corporate culture.

And not to forget: You make your research visible and broaden your network!

That’s important to us

In the best way you have completed a Master and PhD degree (or equivalent) in biotechnology, biochemical engineering, molecular biology, genetics, biochemistry, or similar study.

Strong background in synthetic biology, promoter engineering, molecular biology, biotechnology

Practical experience in synthetic biology and/or molecular biology requested, and scientific interest in bioinformatics applications, yeast cell biology and bioreactor cultivation desired.

Excellent skills in spoken and written English, an organized approach with strong attention to detail and good communication skills with ability to work well in teams.

That’s what you should know

Research will take place in the Institute of Microbiology & Microbial Biotechnology at the Department of Biotechnology of the University of Natural Resources and Life Sciences Vienna (BOKU)

https://boku.ac.at/dbt/immb/research-groups/

The annual gross salary is EUR 61,000.

This corresponds to a monthly net amount of EUR 2,790 (paid 14 times a year).

Start: 2nd of January 2024

Find out more about why acib is the right choice for you: www.acib.at/career

________________________________________

And now it’s your turn! Give us an idea of who you are.

Apply here: short.acib.at/09-2023

Application deadline: 15th of December 2023

Of course, we welcome applicants of all sexes (f/m/x), backgrounds and ages.