Electrostatic potential through charge-integration

This project aims to measure the electrostatic potential of crystalline compounds using electron diffraction. The JUNGFRAU hybrid pixel detector is crucial, combining charge integration with low noise and a wide dynamic range. This allows precise 3D electron diffraction, unveiling hidden structural details. The project develops advanced data acquisition procedures, ensuring high-quality data independent of systematic errors. By combining charge integration with these procedures, the electrostatic potential of chemical compounds can be measured accurately. The electrostatic potential is a fundamental property providing insights into molecule interactions. This method significantly expands the range of analyzable compounds. Applying it to the zeolite catalyst ZSM5 and the anti-cancer drug KP1339 demonstrates its broad applicability. The goal is to develop targeted drugs and more efficient catalysts by understanding the atomic world through electrostatic potential measurements.