Prenatal brain asymmetry and language
Prenatal brain asymmetry and language
Disciplines
Computer Sciences (25%); Medical-Theoretical Sciences, Pharmacy (50%); Linguistics and Literature (25%)
Keywords
-
Language,
Fetal Mri,
Functional Imaging,
Language Localization,
Language Functioning
Title: Is a prenatal asymmetry of the brain predictive for later language localization and functioning? Hintergrund: The brain shows an asymmetry of its structures in most humans. The left hemisphere, especially the left temporal lobe, usually owns more volume and white matter bundles than the right hemisphere. An association between brain asymmetry and localization of language has already been proven. Furthermore, different studies underly the hypothesis that both brain structure and language localization are asociated with language competence. In a previous study, we could demonstrate that most fetuses show a brain asymmetry already in the 20th to 30th gestastional week. We are now interested in the relationship between prenatal asymmetry of brain structures and language localization and language competence in the same children several years later. Aim: The present project aims to shed light on the relationship between prenatal anatomical asymmetry of the brain and later language localization, formation of language-related fiber bundles, and language abilities. Hypotheses: We expect a significant association between prenatal brain asymmetry and later language localization and language competence. Methods: We will investigate 40 healthy children, aged 6 to 16, all of whom had a magnetic resonance imaging in utero between the 20th and 30th gestational week. We will perform a magnetic resonance imaging to investigate language-related white matter bundles and language localization. In addition, we will perform an extensive language assessment in these children. What is new? This study will, for the first time, link prenatal data with later language abilities and language-related fiber bundles. With this knowledge, we hope to find early marker of later language abilities or language deficits.
Research Output
- 1226 Citations
- 18 Publications
- 2 Disseminations
- 2 Scientific Awards
- 1 Fundings
-
2023
Title Fetal temporal sulcus depth asymmetry has prognostic value for language development DOI 10.1038/s42003-023-04503-z Type Journal Article Author Bartha-Doering L Journal Communications Biology Pages 109 Link Publication -
2023
Title Larger corpus callosum volume is favorable for theory of mind development in healthy children DOI 10.1093/cercor/bhad353 Type Journal Article Author Mandl S Journal Cerebral Cortex Pages 11197-11205 Link Publication -
2023
Title Cortical thickness in the right medial frontal gyrus predicts planning performance in healthy children and adolescents DOI 10.3389/fpsyg.2023.1196707 Type Journal Article Author Kollndorfer K Journal Frontiers in Psychology Pages 1196707 Link Publication -
2016
Title Situating the default-mode network along a principal gradient of macroscale cortical organization DOI 10.1073/pnas.1608282113 Type Journal Article Author Margulies D Journal Proceedings of the National Academy of Sciences Pages 12574-12579 Link Publication -
2019
Title Absence of neural speech discrimination in preterm infants at term-equivalent age DOI 10.1016/j.dcn.2019.100679 Type Journal Article Author Bartha-Doering L Journal Developmental Cognitive Neuroscience Pages 100679 Link Publication -
2018
Title Tracing the structural origins of atypical language representation: consequences of prenatal mirror-imaged brain asymmetries in a dizygotic twin couple DOI 10.1007/s00429-018-1717-y Type Journal Article Author Schuler A Journal Brain Structure and Function Pages 3757-3767 Link Publication -
2018
Title When two are better than one: Bilateral mesial temporal lobe contributions associated with better vocabulary skills in children and adolescents DOI 10.1016/j.bandl.2018.06.001 Type Journal Article Author Bartha-Doering L Journal Brain and Language Pages 1-10 Link Publication -
2018
Title Atypical language representation is unfavorable for language abilities following childhood stroke DOI 10.1016/j.ejpn.2018.09.007 Type Journal Article Author Bartha-Doering L Journal European Journal of Paediatric Neurology Pages 102-116 Link Publication -
2018
Title Weaker semantic language lateralization associated with better semantic language performance in healthy right-handed children DOI 10.1002/brb3.1072 Type Journal Article Author Bartha-Doering L Journal Brain and Behavior Link Publication -
2020
Title The impact of hippocampal impairment on task-positive and task-negative language networks in temporal lobe epilepsy DOI 10.1016/j.clinph.2020.10.031 Type Journal Article Author Nenning K Journal Clinical Neurophysiology Pages 404-411 Link Publication -
2020
Title Influence of socioeconomic status on cognitive outcome after childhood arterial ischemic stroke DOI 10.1111/dmcn.14779 Type Journal Article Author Bartha-Doering L Journal Developmental Medicine & Child Neurology Pages 465-471 Link Publication -
2017
Title Assessing Reorganisation of Functional Connectivity in the Infant Brain DOI 10.1007/978-3-319-67561-9_2 Type Book Chapter Author Licandro R Publisher Springer Nature Pages 14-24 -
2017
Title Mens inversus in corpore inverso? Language lateralization in a boy with situs inversus totalis DOI 10.1016/j.bandl.2017.06.005 Type Journal Article Author Schuler A Journal Brain and Language Pages 9-15 Link Publication -
2017
Title Multivariate Manifold Modelling of Functional Connectivity in Developing Language Networks DOI 10.1007/978-3-319-59050-9_25 Type Book Chapter Author Schwartz E Publisher Springer Nature Pages 311-322 -
2019
Title Epilepsy and Bilingualism. A Systematic Review DOI 10.3389/fneur.2019.01235 Type Journal Article Author Bartha-Doering L Journal Frontiers in Neurology -
2020
Title The role of the corpus callosum in language network connectivity in children DOI 10.1111/desc.13031 Type Journal Article Author Bartha-Doering L Journal Developmental Science Link Publication -
2021
Title Effect of corpus callosum agenesis on the language network in children and adolescents DOI 10.1007/s00429-020-02203-6 Type Journal Article Author Bartha-Doering L Journal Brain Structure and Function Pages 701-713 Link Publication -
2021
Title The duration of intrauterine development influences discrimination of speech prosody in infants DOI 10.1111/desc.13110 Type Journal Article Author Alexopoulos J Journal Developmental Science Link Publication
-
2018
Title Press release on language reorganization in childhood Type A press release, press conference or response to a media enquiry/interview -
2019
Title A press release on very early language development Type A press release, press conference or response to a media enquiry/interview
-
2021
Title key-note speaker at the Annual Meeting of the Society for Neonatology and Paediatric Intensive Care (Vienna) Type Personally asked as a key note speaker to a conference Level of Recognition Continental/International -
2021
Title Key note speaker Type Personally asked as a key note speaker to a conference Level of Recognition Continental/International
-
2022
Title BUILD CARE Type Research grant (including intramural programme) Start of Funding 2022 Funder European Commission H2020